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KMID : 0644120040170020041
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Journal of Oriental Gynecology
2004 Volume.17 No. 2 p.41 ~ p.51
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Effects of Gamikyogamhwan on the Ovulation and Ovary in Rats
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Lee Seung-Jun
Cho Han-Baek
Yoo Sim-Keun
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Abstract
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Gamikyogamhwan(GMKGH : 加味交感丸) is used in female infertility, caused by ovulation disorder. An attempt was made to evaluate the influences of GMKGH on the serum concentrations of FSH, LH, and estradiol(E2), the histological changes of ovary and the immunohistochemic-al staining for AT2 receptor in ovary of rats. The results of the study were as follows : 1. In blood FSH level, experimental group as compared with control group showed no efficacy. 2. In blood LH level, experimental group as compared with control group showed no efficacy. 3. Blood E2 level significantly increased in experimental group as compared with control group. 4. In histological observations of ovary, ovulation significantly increased in experimental group as compared control group. 5. In observations of immunohistochemical staining for AT2 receptor in ovary, there is no difference between control group and experimental group. According to these results, it can be concluded that GMKGH influences ovary to increase the ovulation of rats.
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KEYWORD
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Gamikyogamhwan, Ovulation, Ovary
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